Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305063 | 0.96 | DGKA (0.59) | DGKAMAPTDNM1CYP3A4TSHR | |
| Ethylene SCHEMBL28281233 | 0.93 | DGKA (0.55) | DGKAMAPTDNM1CYP3A4TSHR | |
| SCHEMBL873505 | 0.91 | DGKA (0.68) | DGKAMAPTDNM1CYP3A4TSHR | |
| SCHEMBL28098427 | 0.89 | DGKA (0.52) | DGKAMAPTDNM1CYP3A4TSHR | |
| SCHEMBL120186 | 0.89 | DGKA (0.71) | DGKAMAPTDNM1TSHRLMNA | |
| SCHEMBL2032699 | 0.89 | DGKA (0.71) | DGKAMAPTDNM1TSHRLMNA | |
| SCHEMBL2396768 | 0.89 | DGKA (0.71) | DGKAMAPTDNM1TSHRLMNA | |
| SCHEMBL19409845 | 0.89 | DGKA (0.71) | DGKAMAPTDNM1TSHRLMNA | |
| SCHEMBL2397395 | 0.89 | DGKA (0.71) | DGKAMAPTDNM1TSHRLMNA | |
| SCHEMBL37144 | 0.89 | DGKA (0.71) | DGKAMAPTDNM1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109652424-B | A kind of methods and applications that somatic embryos directly occur | 山东农业大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-109652424-A | A kind of methods and applications that somatic embryos directly occur | 山东农业大学 | 2019-04-19 | — | — | CN | disclosed |