Cyanide

Cyanide

SCHEMBL28294768

C.C#N.c1ccc2c(c1)ccc1cc[nH]c12

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.48
AHR P35869 2/20 0.44
KDM4E B2RXH2 1/20 0.43
RAB9A P51151 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP2A6 P11509 1/20 0.42
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KIF11 P52732 1/20 0.41
TRPA1 O75762 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ITGB2 P05107 1/20 0.40
ICAM1 P05362 1/20 0.40
ITGAL P20701 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanide SCHEMBL28891109 0.98 PARP1 (0.50) PARP1AHRKDM4ERAB9ASIRT2
SCHEMBL305400 0.92 PARP1 (0.56) PARP1AHRKDM4ERAB9ASIRT2
Bromide SCHEMBL29578396 0.90 PARP1 (0.54) PARP1AHRKDM4ERAB9ASIRT2
Iodide SCHEMBL29375711 0.90 PARP1 (0.54) PARP1AHRKDM4ERAB9ASIRT2
Ammonia Solution, Strong SCHEMBL30759442 0.90 PARP1 (0.54) PARP1AHRKDM4ERAB9ASIRT2
Naphthalene SCHEMBL28275037 0.90 PARP1 (0.54) PARP1AHRKDM4ERAB9ASIRT2
Hydrogen Peroxide SCHEMBL30104733 0.88 PARP1 (0.52) PARP1AHRKDM4ERAB9ASIRT2
SCHEMBL29467418 0.82 HPRT1 (0.58) PARP1AHRKDM4ERAB9ASIRT2
SCHEMBL28733279 0.82 HPRT1 (0.58) PARP1AHRKDM4ERAB9ASIRT2
SCHEMBL29379427 0.82 HPRT1 (0.58) PARP1AHRKDM4ERAB9ASIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796779-A A kind of preparation method of seven methines benzindole cyanine dye 中国科学院宁波材料技术与工程研究所 2019-05-24 CN claimed
CN-109796780-A Seven methine benzindole cyanine dyes of one kind and its preparation method and application 中国科学院宁波材料技术与工程研究所 2019-05-24 CN claimed
CN-109796779-A A kind of preparation method of seven methines benzindole cyanine dye 中国科学院宁波材料技术与工程研究所 2019-05-24 CN disclosed
CN-109796779-A A kind of preparation method of seven methines benzindole cyanine dye 中国科学院宁波材料技术与工程研究所 2019-05-24 CN disclosed
CN-109796780-A Seven methine benzindole cyanine dyes of one kind and its preparation method and application 中国科学院宁波材料技术与工程研究所 2019-05-24 CN disclosed
CN-109796780-A Seven methine benzindole cyanine dyes of one kind and its preparation method and application 中国科学院宁波材料技术与工程研究所 2019-05-24 CN disclosed
CN-109796780-A Seven methine benzindole cyanine dyes of one kind and its preparation method and application 中国科学院宁波材料技术与工程研究所 2019-05-24 CN disclosed