Hydrogen Peroxide

Hydrogen Peroxide

SCHEMBL30104733

OO.c1ccc2c(c1)ccc1cc[nH]c12

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.52
KEAP1 Q14145 1/20 0.50
AHR P35869 2/20 0.47
CSNK2A2 P19784 1/20 0.46
CSNK2B P67870 1/20 0.46
CSNK2A1 P68400 1/20 0.46
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 1/20 0.46
RAB9A P51151 1/20 0.46
SIRT2 Q8IXJ6 1/20 0.46
SIRT1 Q96EB6 1/20 0.46
PDPK1 O15530 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305400 0.96 PARP1 (0.56) PARP1KEAP1AHRCSNK2A2CSNK2B
Naphthalene SCHEMBL28275037 0.93 PARP1 (0.54) PARP1KEAP1AHRCSNK2A2CSNK2B
Iodide SCHEMBL29375711 0.93 PARP1 (0.54) PARP1KEAP1AHRCSNK2A2CSNK2B
Ammonia Solution, Strong SCHEMBL30759442 0.93 PARP1 (0.54) PARP1KEAP1AHRCSNK2A2CSNK2B
Bromide SCHEMBL29578396 0.93 PARP1 (0.54) PARP1KEAP1AHRCSNK2A2CSNK2B
Cyanide SCHEMBL28891109 0.89 PARP1 (0.50) PARP1KEAP1AHRCSNK2A2CSNK2B
Cyanide SCHEMBL28294768 0.88 PARP1 (0.48) PARP1KEAP1AHRCSNK2A2CSNK2B
SCHEMBL1501494 0.85 HPRT1 (0.58) PARP1KEAP1AHRALDH1A1HSD17B10
SCHEMBL31300209 0.85 HPRT1 (0.58) PARP1KEAP1AHRALDH1A1HSD17B10
SCHEMBL28733279 0.85 HPRT1 (0.58) PARP1KEAP1AHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142766-B Benzoindole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2022-12-06 CN claimed
CN-112142766-B Benzoindole hydrogen peroxide fluorescent probe and preparation method thereof 南通大学 2022-12-06 CN disclosed