Toluene

Toluene

SCHEMBL28294826

Cc1ccccc1.Cn1ccnc1.S

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 3/20 0.60
QPCTL Q9NXS2 2/20 0.60
NFKB1 P19838 1/20 0.60
HSD17B10 Q99714 1/20 0.60
CYP19A1 P11511 7/20 0.44
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
ACHE P22303 1/20 0.44
CYP3A4 P08684 2/20 0.44
CYP11B1 P15538 5/20 0.42
CYP11B2 P19099 5/20 0.42
CYP17A1 P05093 3/20 0.41
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
TBXAS1 P24557 1/20 0.40
CYP4Z1 Q86W10 1/20 0.40
CYP26A1 O43174 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL5014303 0.98 QPCT (0.62) QPCTQPCTLNFKB1HSD17B10CYP19A1
Toluene SCHEMBL27720702 0.96 QPCT (0.60) QPCTQPCTLNFKB1HSD17B10CYP19A1
Toluene SCHEMBL4300043 0.88 QPCT (0.50) QPCTQPCTLNFKB1HSD17B10CYP19A1
M-Xylene SCHEMBL29245042 0.84 NFKB1 (0.60) QPCTQPCTLNFKB1HSD17B10CYP19A1
1-Methylimidazole SCHEMBL8002456 0.82 QPCT (0.88) QPCTQPCTLNFKB1HSD17B10CYP19A1
Phenol SCHEMBL11630320 0.80 QPCT (0.60) QPCTQPCTLNFKB1HSD17B10CYP19A1
1-Methylimidazole SCHEMBL6004970 0.80
Naphthalene SCHEMBL28099094 0.79 QPCT (0.65) QPCTQPCTLNFKB1HSD17B10CYP19A1
1-Methylimidazole SCHEMBL21182316 0.78 QPCT (0.58) QPCTQPCTLNFKB1HSD17B10CYP19A1
1-Methylimidazole SCHEMBL28099737 0.78 QPCT (0.58) QPCTQPCTLNFKB1HSD17B10CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790292-A Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2019-05-21 CN disclosed