Hydrazine

Hydrazine

SCHEMBL28294836

Cc1cc(C)c([C]=O)c(C)c1.NN

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 4/20 0.36
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.35
F2 P00734 2/20 0.33
PRSS1 P07477 2/20 0.33
PRSS2 P07478 2/20 0.33
PRSS3 P35030 2/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96536 0.95 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
Phosphine SCHEMBL28104721 0.92 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL28106359 0.92 RAPGEF4 (0.38) RAPGEF4ALDH1A1KDM4ELMNAGAA
Formaldehyde SCHEMBL28295617 0.90 RAPGEF4 (0.36) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL28150826 0.80 TSHR (0.33) RAPGEF4TSHR
Anthraquinone SCHEMBL28288400 0.77 ELANE (0.52) ALDH1A1KDM4ELMNAMAPTTSHR
SCHEMBL27458877 0.75 IDO1 (0.35) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL1535608 0.72 POLB (0.46) ALDH1A1LMNATSHRHSD17B10CYP3A4
SCHEMBL18050282 0.71 RAPGEF4 (0.43) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL7067381 0.71 RAPGEF4 (0.43) RAPGEF4ALDH1A1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689617-A Fluorene derivative, organic light emitting device using the same, and method of manufacturing the same 株式会社LG化学 2019-04-26 CN disclosed