O-Tolylamine

O-Tolylamine

SCHEMBL28294975

Cc1ccc(C)c([N+](=O)[O-])c1.Cc1ccccc1N

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.62
CYP3A4 P08684 5/20 0.57
ALDH1A1 P00352 4/20 0.57
RECQL P46063 1/20 0.57
HSD17B10 Q99714 1/20 0.55
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
TDP1 Q9NUW8 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 2/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
RAB9A P51151 2/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29613904 0.84 TSHR (0.72) TSHRCYP3A4ALDH1A1RECQLHSD17B10
SCHEMBL171914 0.84 TSHR (0.72) TSHRCYP3A4ALDH1A1RECQLHSD17B10
4-Nitrotoluene SCHEMBL28210309 0.78 HSD17B10 (0.64) TSHRCYP3A4ALDH1A1HSD17B10TDP1
SCHEMBL29037931 0.77 TSHR (0.77) TSHRCYP3A4ALDH1A1TDP1SMN1; SMN2
SCHEMBL11901213 0.77 TSHR (0.62) TSHRCYP3A4ALDH1A1RECQLHSD17B10
O-Tolylamine SCHEMBL25436024 0.77 TDP1 (0.71) TSHRCYP3A4ALDH1A1RECQLHSD17B10
Nitrophenolate SCHEMBL27262880 0.77 TSHR (0.53) TSHRCYP3A4ALDH1A1RECQLHSD17B10
SCHEMBL98492 0.77 TSHR (1.00) TSHRCYP3A4ALDH1A1RECQLHSD17B10
2,5-Xylidine SCHEMBL27949130 0.77 TDP1 (0.77) CYP3A4ALDH1A1HSD17B10TDP1SMN1; SMN2
Ethylene Glycol SCHEMBL20567147 0.76 TSHR (0.60) TSHRCYP3A4ALDH1A1RECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890206-A Anil that 4- is substituted and its plant pathogenic microorganisms being not intended in confrontation are with the purposes on cover crop 印度商皮埃企业有限公司 2019-06-14 CN disclosed