SCHEMBL98492

SCHEMBL98492

Cc1ccc(N)c([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 1.00
CYP3A4 P08684 6/20 0.67
TDP1 Q9NUW8 6/20 0.64
ALDH1A1 P00352 4/20 0.64
MEN1 O00255 2/20 0.64
POLB P06746 2/20 0.64
KMT2A Q03164 2/20 0.64
ALOX15 P16050 2/20 0.64
MAPT P10636 1/20 0.64
LMNA P02545 1/20 0.55
PKM P14618 1/20 0.54
ACHE P22303 2/20 0.50
HSD17B10 Q99714 1/20 0.50
GPR35 Q9HC97 1/20 0.50
RECQL P46063 1/20 0.50
KAT2B Q92831 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3172274 0.98 TSHR (0.96) TSHRCYP3A4TDP1ALDH1A1MEN1
Nitrogen SCHEMBL10942334 0.94 TSHR (0.89) TSHRCYP3A4TDP1ALDH1A1MEN1
SCHEMBL11595175 0.93 TSHR (0.86) TSHRCYP3A4TDP1ALDH1A1MEN1
4-Chloro-2-Nitroaniline SCHEMBL11378427 0.89 TSHR (0.80) TSHRCYP3A4TDP1ALDH1A1MEN1
SCHEMBL29037931 0.88 TSHR (0.77) TSHRCYP3A4TDP1ALDH1A1MEN1
SCHEMBL7521966 0.88 TSHR (0.77) TSHRCYP3A4TDP1ALDH1A1MEN1
SCHEMBL5952772 0.85 TDP1 (0.79) TSHRCYP3A4TDP1ALDH1A1MEN1
Acetoacetic Acid SCHEMBL11807528 0.84 TSHR (0.71) TSHRCYP3A4TDP1ALDH1A1MEN1
SCHEMBL31365116 0.83 TSHR (0.71) TSHRCYP3A4TDP1ALDH1A1MEN1
SCHEMBL138990 0.83 TSHR (0.71) TSHRCYP3A4TDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12575328-B2 High thermal stability by doping of oxide capping layer for spin torque transfer (STT) magnetic random access memory (MRAM) applications TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-03-10 US claimed
US-20250388480-A1 METHOD FOR SELECTING CATALYST, CATALYST, AND METHOD FOR PRODUCING CATALYST ENEOS CORP (JP) 2025-12-25 US claimed
EP-4552737-A1 AMMONIA SYNTHESIS CATALYST AND AMMONIA SYNTHESIS METHOD ENEOS Corporation (JP) 2025-05-14 EP claimed
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-119192897-B Toluidine red pigment for building coating and preparation method thereof 蓬莱新光颜料化工有限公司 2025-01-24 CN claimed
CN-119192897-A Toluidine red pigment for building coating and preparation method thereof 蓬莱新光颜料化工有限公司 2024-12-27 CN claimed
CN-118127540-A Method for preparing cyclohexyl methyl ether by electrocatalytic conversion of guaiacol by metal supported catalyst 中国科学院化学研究所 2024-06-04 CN claimed
CN-117599168-A Chlorin modified metal oxide nano enzyme diagnosis and treatment system and preparation method and application thereof 徐州医科大学 2024-02-27 CN claimed
CN-115772336-B Preparation of purple organic pigment 双乐颜料泰兴市有限公司 2024-02-20 CN claimed
CN-115785695-B Preparation of green organic pigment 双乐颜料泰兴市有限公司 2024-02-20 CN claimed
EP-0079303-A2 Stabilized covering form of CI pigment yellow 74 CIBA-GEIGY AG (CH) 1983-05-18 EP claimed
EP-0076681-A1 Soldering device and method RAYCHEM CORPORATION (a California corporation) (US) 1983-04-13 EP claimed
US-4374250-A CYCLIZATION, SELENIUM CATALYST OSAKA MUNICIPAL GOVERNMENT (JP) 1983-02-15 US claimed
EP-0027658-B1 PROCESS FOR THE PRODUCTION OF 3-NITRO-4-AMINOTOLUENE BAYER AG (DE) 1982-05-26 EP claimed
EP-0047337-A1 Process for the manufacture of 3-nitro-4-amino-toluene BAYER AG (DE) 1982-03-17 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
EP-0027658-A1 Process for the production of 3-nitro-4-aminotoluene BAYER AG (DE) 1981-04-29 EP claimed
US-4178455-A FROM AROMATIC NITRO COMPOUND, ALCOHOL AND CARBON MONOXIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1979-12-11 US claimed
US-4036770-A Stabilization of hydrocracked oils with amino nitrophenols MOBIL OIL CORPORATION (US) 1977-07-19 US claimed
US-3991044-A Process for improving lightfastness of an azo pigment by heat treatment HERCULES INCORPORATED (US) 1976-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388480-A1 METHOD FOR SELECTING CATALYST, CATALYST, AND METHOD FOR PRODUCING CATALYST ACHE, COMT, CYP2E1 TSHR 2052/4885CYP3A4 9/4885TDP1 548/4885
US-12575328-B2 High thermal stability by doping of oxide capping layer for spin torque transfer (STT) magnetic random access memory (MRAM) applications RNMT, PRDM9, TIMM9 TSHR 3128/4885CYP3A4 3877/4885TDP1 4392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.