Phenetole

Phenetole

SCHEMBL28295089

CCOc1ccccc1.COC(=O)CN

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.52
HTT P42858 1/20 0.49
RAB9A P51151 4/20 0.48
NPC1 O15118 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HPGD P15428 1/20 0.48
ALDH1A1 P00352 2/20 0.47
PARP10 Q53GL7 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 2/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 2/20 0.46
CNR2 P34972 1/20 0.46
PLK1 P53350 1/20 0.45
POLB P06746 1/20 0.45
CYP1A2 P05177 1/20 0.45
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cadaverine Tartrate SCHEMBL28295190 0.91 LTA4H (0.44) LTA4HHTTRAB9ANPC1SMN1; SMN2
Anisole SCHEMBL28296887 0.84 CA4 (0.54) LTA4HHTTRAB9ANPC1SMN1; SMN2
Phenetole SCHEMBL28263651 0.83 HTT (0.56) LTA4HHTTRAB9ANPC1SMN1; SMN2
Phenetole SCHEMBL27945108 0.81 LTA4H (0.63) LTA4HRAB9ANPC1SMN1; SMN2HPGD
Phenetole SCHEMBL28201837 0.80 LTA4H (0.61) LTA4HRAB9ANPC1SMN1; SMN2HPGD
Biphenyl SCHEMBL3991647 0.80 POLB (0.47) HTTRAB9ANPC1SMN1; SMN2HPGD
Phenetole SCHEMBL29242129 0.79 LTA4H (0.65) LTA4HRAB9ANPC1SMN1; SMN2HPGD
Phenetole SCHEMBL8364233 0.79 LTA4H (0.65) LTA4HRAB9ANPC1SMN1; SMN2HPGD
Phenetole SCHEMBL28029045 0.79 LTA4H (0.65) LTA4HRAB9ANPC1SMN1; SMN2HPGD
Phenetole SCHEMBL11643773 0.79 LTA4H (0.71) LTA4HRAB9ANPC1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109734617-A A kind of method for splitting replacing aromatic ring phenylglycine aliphatic alcohol ester 华东理工大学 2019-05-10 CN disclosed