Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.82 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.82 |
| ▸ | PNMT | P11086 | 2/20 | 0.82 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.82 |
| ▸ | PRMT7 | Q9NVM4 | 3/20 | 0.79 |
| ▸ | AHCY | P23526 | 3/20 | 0.76 |
| ▸ | NADK | O95544 | 1/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.73 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.73 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.72 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.72 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.72 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.72 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.72 |
| ▸ | INMT | O95050 | 1/20 | 0.72 |
| ▸ | NSD2 | O96028 | 1/20 | 0.72 |
| ▸ | NNMT | P40261 | 1/20 | 0.72 |
| ▸ | HNMT | P50135 | 1/20 | 0.72 |
| ▸ | WDR5 | P61964 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829520 | 1.00 | DOT1L (0.82) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL30216716 | 0.94 | DOT1L (0.83) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL6897966 | 0.94 | DOT1L (0.83) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL4884765 | 0.93 | DOT1L (0.81) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL998091 | 0.91 | AHCY (0.79) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL2115821 | 0.91 | AHCY (0.79) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL14174635 | 0.90 | DOT1L (1.00) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL5055464 | 0.90 | DOT1L (1.00) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL1490901 | 0.90 | DOT1L (0.84) | DOT1LDNMT3BPNMTDNMT1PRMT7 | |
| SCHEMBL16272276 | 0.90 | DOT1L (1.00) | DOT1LDNMT3BPNMTDNMT1PRMT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4324928-A1 | SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION | Universität Basel (CH) | 2024-02-21 | — | — | EP | claimed |
| EP-4324928-A1 | SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION | Universität Basel (CH) | 2024-02-21 | — | — | EP | disclosed |
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |
| EP-1874790-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH Aachen (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108678-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2006-10-19 | — | — | WO | disclosed |
| EP-1712557-A1 | New s-adenosyl-L-methionine analogues with extended activated groups for transfer by methyltransferases | RWTH Aachen (DE) | 2006-10-18 | — | — | EP | disclosed |
| EP-0233031-B1 | METHYLTHIORIBOSE ANALOGUES, THEIR PREPARATION AND USE AS MEDICINAL AGENTS AND BIOCIDES | STATE OF OREGON BY AND THROUGH OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OREGON HEALTH SC. UNIV. AND OREGON STATE UNIV. (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4820692-A | PARASITICIDES, FUNGICIDES | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND OREGON STATE UNIVERSITY (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0233031-A2 | Methylthioribose analogues, their preparation and use as medicinal agents and biocides | STATE OF OREGON BY AND THROUGH OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OREGON HEALTH SC. UNIV. AND OREGON STATE UNIV. (US) | 1987-08-19 | — | — | EP | disclosed |