Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17839436 | 0.78 | HTT (0.43) | HTTALDH1A1KDM4ECA1CA2 | |
| SCHEMBL3971916 | 0.78 | ALDH1A1 (0.47) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2639975 | 0.78 | HTT (0.43) | HTTALDH1A1KDM4ECA1CA2 | |
| SCHEMBL11119057 | 0.78 | HTT (0.43) | HTTALDH1A1KDM4ECA1CA2 | |
| SCHEMBL14267908 | 0.78 | BACE1 (0.55) | HTTALDH1A1KDM4ECA1CA2 | |
| SCHEMBL30374767 | 0.78 | HTT (0.43) | HTTALDH1A1KDM4ECA1CA2 | |
| SCHEMBL6664318 | 0.74 | ADORA2A (0.38) | HTTALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL3967055 | 0.74 | HTT (0.40) | HTTALDH1A1KDM4ECA1CA2 | |
| SCHEMBL4725838 | 0.71 | ALDH1A1 (0.50) | HTTALDH1A1KDM4EGAALMNA | |
| SCHEMBL29365630 | 0.70 | ALDH1A1 (0.56) | HTTALDH1A1KDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109627212-B | Diacid monomer and preparation method thereof, and polyamide and preparation method thereof | 吉林大学 | 2020-03-10 | — | — | CN | disclosed |
| CN-109627212-A | A kind of diacid monomer and preparation method thereof and polyamide and preparation method thereof | 吉林大学 | 2019-04-16 | — | — | CN | disclosed |