SCHEMBL28295306

SCHEMBL28295306

CCCCCCCS(=O)(=O)O.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
NAAA Q02083 1/20 0.41
S1PR2 O95136 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
EPHX2 P34913 1/20 0.41
MMP1 P03956 1/20 0.41
MMP9 P14780 1/20 0.41
MMP13 P45452 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HTT P42858 2/20 0.40
PTGS2 P35354 1/20 0.40
CYP3A4 P08684 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
EPHX1 P07099 3/20 0.40
GHSR Q92847 1/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28116920 1.00 CES2 (0.42) CES2CES1NAAAS1PR2S1PR1
Heptane SCHEMBL27980719 0.90 CES2 (0.47) CES2CES1NAAAALDH1A1HTT
Heptane SCHEMBL27980716 0.90 CES2 (0.47) CES2CES1NAAAALDH1A1HTT
SCHEMBL28225685 0.86 CYP3A4 (0.46) CES2CES1ALDH1A1HTTCYP3A4
Biphenyl SCHEMBL27876466 0.84 PTPN1 (0.48) NAAAS1PR2S1PR1S1PR3EPHX2
Benzene SCHEMBL11150225 0.84 EPHX2 (0.51) CES2CES1S1PR2S1PR1S1PR3
Benzene SCHEMBL28758814 0.84 EPHX2 (0.51) CES2CES1S1PR2S1PR1S1PR3
Benzene SCHEMBL27649746 0.84 EPHX2 (0.51) CES2CES1S1PR2S1PR1S1PR3
Benzene SCHEMBL27649739 0.84 EPHX2 (0.51) CES2CES1S1PR2S1PR1S1PR3
Benzene SCHEMBL112147 0.84 EPHX2 (0.51) CES2CES1S1PR2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106183520-B Original edition of lithographic printing plate and its printing process 富士胶片株式会社 2019-05-17 CN disclosed