Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | FEN1 | P39748 | 8/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 7/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728208 | 0.86 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9078297 | 0.85 | PDE4B (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17114462 | 0.84 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19849257 | 0.81 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27861005 | 0.81 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1733443 | 0.81 | NPC1 (0.71) | FEN1ERCC5PTPN1NPC1ALDH1A1 | |
| SCHEMBL17317414 | 0.80 | TSHR (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8239580 | 0.77 | CA9 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27517664 | 0.77 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11701143 | 0.76 | CA12 (0.60) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790152-A | The diagnosis of neurotensin receptor associated disease treats and prevents | 埃朗根-纽伦堡 弗里德里希-亚历山大大学 | 2019-05-21 | — | — | CN | disclosed |