Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711619 | 0.83 | USP2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL6711615 | 0.83 | USP2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL24724667 | 0.80 | CYP2D6 (0.46) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL10902892 | 0.78 | CYP1A2 (0.41) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL8494529 | 0.74 | MAPT (0.57) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL8494526 | 0.74 | MAPT (0.57) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL1855483 | 0.73 | CYP2D6 (0.46) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL15785939 | 0.72 | CYP2D6 (0.48) | SMN1; SMN2KDM4EL3MBTL1ALDH1A1CYP2D6 | |
| SCHEMBL29933293 | 0.72 | CYP2D6 (0.48) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL10673356 | 0.71 | MAPT (0.54) | SMN1; SMN2NPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109666950-A | method for electrochemically synthesizing tetrazole compound | 浙江工业大学 | 2019-04-23 | — | — | CN | disclosed |