Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTH | P32929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711619 | 1.00 | USP2 (0.56) | USP2G6PC1MAOAMAOBNR4A1 | |
| SCHEMBL28295586 | 0.83 | SMN1; SMN2 (0.51) | USP2G6PC1NPC1RAB9AMEN1 | |
| SCHEMBL3943697 | 0.83 | USP2 (0.70) | USP2G6PC1MAOAMAOBNR4A1 | |
| SCHEMBL3943694 | 0.83 | USP2 (0.70) | USP2G6PC1MAOAMAOBNR4A1 | |
| SCHEMBL14517008 | 0.82 | USP2 (0.62) | USP2G6PC1MAOAMAOBNR4A1 | |
| SCHEMBL22862043 | 0.82 | USP2 (0.62) | USP2G6PC1MAOAMAOBNR4A1 | |
| SCHEMBL24724667 | 0.80 | CYP2D6 (0.46) | USP2MAOAMAOBNPC1RAB9A | |
| SCHEMBL10902892 | 0.78 | CYP1A2 (0.41) | USP2MAOAMAOBNPC1RAB9A | |
| SCHEMBL9768784 | 0.73 | USP2 (0.57) | USP2G6PC1MAOAMAOBNR4A1 | |
| SCHEMBL9768782 | 0.73 | USP2 (0.57) | USP2G6PC1MAOAMAOBNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | ALMSTEAD JI-IN KIM (US) | 2004-03-18 | — | — | US | claimed |
| US-6660737-B2 | Antihypoxic agents | THE PROCTER & GAMBLE COMPANY | 2003-12-09 | — | — | US | claimed |
| US-20030092716-A1 | Medicinal uses of hydrazones | THE PROCTER & GAMBLE COMPANY | 2003-05-15 | — | — | US | claimed |
| US-20040053977-A1 | Medicinal uses of hydrazones | ALMSTEAD JI-IN KIM (US) | 2004-03-18 | — | — | US | disclosed |
| US-6660737-B2 | Antihypoxic agents | THE PROCTER & GAMBLE COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030092716-A1 | Medicinal uses of hydrazones | THE PROCTER & GAMBLE COMPANY | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | PGF, VEGFA, TEK | USP2 3452/4885G6PC1 1699/4885MAOA 1156/4885 |
| US-20030092716-A1 | Medicinal uses of hydrazones | EPOR, VEGFA, HIF1A | USP2 3725/4885G6PC1 1336/4885MAOA 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.