Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29056112 | 0.71 | — | — | |
| SCHEMBL3256630 | 0.70 | IDO1 (0.52) | PNMTIDO1ANPEPCA1CA2 | |
| SCHEMBL25660619 | 0.67 | IDO1 (0.39) | PNMTIDO1ANPEPCA1CA2 | |
| SCHEMBL25662343 | 0.67 | IDO1 (0.39) | PNMTIDO1ANPEPCA1CA2 | |
| SCHEMBL14317351 | 0.67 | IDO1 (0.39) | PNMTIDO1ANPEPCA1CA2 | |
| SCHEMBL28071032 | 0.67 | PRMT5 (0.33) | IDO1 | |
| SCHEMBL18938161 | 0.66 | IDO1 (0.41) | IDO1ANPEPCA1CA2 | |
| SCHEMBL11555929 | 0.63 | PLAU (0.46) | IDO1ANPEPCA1CA2 | |
| SCHEMBL8266115 | 0.63 | CA1 (0.34) | PNMTIDO1ANPEPCA1CA2 | |
| SCHEMBL15203069 | 0.63 | GRM7 (0.35) | IDO1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689639-A | Spirolactams as ROCK inhibitor | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |