Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.65 |
| ▸ | PI4KA | P42356 | 3/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL28230309 | 0.94 | PNP (0.63) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL2530081 | 0.92 | PNP (0.77) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL1831281 | 0.92 | PNP (0.77) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL1263327 | 0.92 | PNP (0.77) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL6307918 | 0.92 | PNP (0.77) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL641789 | 0.91 | PNP (0.79) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL3820889 | 0.84 | PNP (0.60) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL5542713 | 0.84 | PI4KA (0.79) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Guanine SCHEMBL16552675 | 0.83 | PNP (0.62) | PNPXDHGRIA1GRIA2GRIA3 | |
| Guanine SCHEMBL27753678 | 0.83 | PNP (0.79) | PNPGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109831916-A | The composition and method for treating hungtington's chorea | 沃雅戈治疗公司 | 2019-05-31 | — | — | CN | disclosed |