Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.79 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanine SCHEMBL27753678 | 0.91 | PNP (0.79) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL28295810 | 0.91 | PNP (0.65) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL28068968 | 0.90 | PNP (0.63) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL27782399 | 0.90 | PNP (0.63) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL28171868 | 0.89 | PNP (0.93) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL986801 | 0.89 | PNP (1.00) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL1264884 | 0.89 | PNP (1.00) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL5260 | 0.89 | PNP (1.00) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL16552675 | 0.89 | PNP (0.62) | PNPGRIA1GRIA2GRIA3GRIA4 | |
| Guanine SCHEMBL7211609 | 0.88 | PNP (0.60) | PNPGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658797-A | Compositions and methods for modulating RNA | RANA医疗有限公司 | 2016-06-08 | — | — | CN | claimed |
| US-9186399-B2 | Immune stimulatory oligonucleotide analogs containing modified sugar moieties | AdiutTide Pharmaceuticals GmbH (DE) | 2015-11-17 | — | — | US | claimed |
| EP-2197488-B1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | ADIUTIDE PHARMACEUTICALS GMBH (DE) | 2014-05-07 | — | — | EP | claimed |
| US-20110098456-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | ADIUTIDE PHARMACEUTICALS GMBH (DE) | 2011-04-28 | — | — | US | claimed |
| JP-2011500014-A | — | — | 2011-01-06 | — | — | JP | claimed |
| CN-101820908-A | Immunostimulatory oligonucleotide analogs comprising modified sugar moieties | COLEY PHARM GMBH | 2010-09-01 | — | — | CN | claimed |
| EP-2197488-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | Coley Pharmaceuticals GmbH (DE) | 2010-06-23 | — | — | EP | claimed |
| WO-2009047610-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | COLEY PHARMACEUTICAL GMBH (DE) | 2009-04-16 | — | — | WO | claimed |
| CN-100379879-C | Method for measuring DNA polymerization and applications of method | CAVIDI TECH AB (SE) | 2008-04-09 | — | — | CN | claimed |
| CN-101027389-A | Method for preparing L-arginine, L-ornithine or L-citrulline | KYOWA HAKKO KOGYO KK (JP) | 2007-08-29 | — | — | CN | claimed |
| EP-3724225-A1 | ANTI-CCT5 BINDING MOLECULES AND METHODS OF USE THEREOF | Juno Therapeutics, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| CN-110418647-A | The nucleic acid modifying enzyme and its application method of RNA guidance | UNIV CALIFORNIA | 2019-11-05 | — | — | CN | disclosed |
| CN-110079588-A | For the method for nucleic acid amplification, composition, system, instrument and kit | 生命技术公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-110055247-A | SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING AMINO ACID BACKBONE | 株式会社博纳克 | 2019-07-26 | — | — | CN | disclosed |
| CN-110023494-A | RNA-GUIDED NUCLEIC ACID MODIFYING ENZYMES AND METHODS OF USE THEREOF | 加利福尼亚大学董事会 | 2019-07-16 | — | — | CN | disclosed |
| US-20060211644-A1 | Immunostimulatory oligonucleotides | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-09-21 | — | — | US | disclosed |
| WO-2006091915-A2 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| US-20060019923-A1 | Methods and compositions for inducing innate immune responses | COLEY PHARMACEUTICAL GROUP, LTD. (CA) | 2006-01-26 | — | — | US | disclosed |
| CN-1489477-A | Conjugates of glycosylated/galactosylated peptides, bifunctional linkers, and nucleotide monomers/polymers, and related compositions and methods of use | — | 2004-04-14 | — | — | CN | disclosed |
| CN-1425023-A | Transgenic mice containing TRP gene disruptions | DELTAGEN INC (US) | 2003-06-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098456-A1 | IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES | NT5C2, TLR3, TLR9 | PNP 36/4885GRIA1 1897/4885GRIA2 2221/4885 |
| US-20060019923-A1 | Methods and compositions for inducing innate immune responses | TLR3, MYD88, TLR1 | PNP 3194/4885GRIA1 1662/4885GRIA2 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.