SCHEMBL28295834

SCHEMBL28295834

O=C1NC(=O)c2c(CS)ccc3cccc1c23

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 3/20 0.58
NPSR1 Q6W5P4 2/20 0.43
GSK3B P49841 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CASP7 P55210 2/20 0.38
RGS12 O14924 1/20 0.38
USP2 O75604 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
CYP2C9 P11712 1/20 0.38
APEX1 P27695 1/20 0.38
CASP1 P29466 1/20 0.38
BRCA1 P38398 1/20 0.38
MTOR P42345 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16116423 0.86 PARP1 (0.59) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL11204216 0.84 PARP1 (0.58) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL11210705 0.83 PARP1 (0.56) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL28257840 0.82 PARP1 (0.54) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL8205632 0.82 PARP1 (0.54) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL19895278 0.82 PARP1 (0.54) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL8518060 0.81 PARP1 (0.53) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL28507256 0.81 PARP1 (0.53) PARP1NPSR1GSK3BMEN1KMT2A
Hydrochloric Acid SCHEMBL28259370 0.81 PARP1 (0.53) PARP1NPSR1GSK3BMEN1KMT2A
SCHEMBL9556433 0.80 PARP1 (0.51) PARP1NPSR1GSK3BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109929106-A A kind of fluorescence probe and its preparation method and application detecting thiocyanate radical 济南大学 2019-06-25 CN disclosed
CN-109929106-A A kind of fluorescence probe and its preparation method and application detecting thiocyanate radical 济南大学 2019-06-25 CN disclosed
CN-109705292-A A kind of organosilicon macromolecule fluorescence probe detecting thiocyanate radical and its synthesis and application 济南大学 2019-05-03 CN disclosed
CN-109705292-A A kind of organosilicon macromolecule fluorescence probe detecting thiocyanate radical and its synthesis and application 济南大学 2019-05-03 CN disclosed