Imidazole

Imidazole

SCHEMBL28295853

Fc1ccncc1F.c1c[nH]cn1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
FKBP5 Q13451 1/20 0.54
LOXL2 Q9Y4K0 1/20 0.39
NUDT1 P36639 2/20 0.39
ACHE P22303 1/20 0.31
CHUK O15111 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518741 0.82
SCHEMBL3717170 0.82
Imidazole SCHEMBL27412080 0.75 ALDH1A1 (0.54) ALDH1A1FKBP5
Imidazole SCHEMBL28744226 0.74 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL2635292 0.74
Imidazole SCHEMBL30382963 0.74
Imidazole SCHEMBL19028065 0.74 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL1331382 0.74
Imidazole SCHEMBL2684565 0.74 ALDH1A1 (1.00) ALDH1A1FKBP5
Imidazole SCHEMBL897 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232600-B Indolin-2-one and 1,3- dihydro-pyrrole simultaneously [3,2-c] pyridin-2-ones derivative 豪夫迈·罗氏有限公司 2019-05-14 CN disclosed