Succinimide

Succinimide

SCHEMBL28295942

O=C1CCC(=O)N1.[O]C(=O)c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 6/20 0.46
DDB1 Q16531 5/20 0.46
NPC1 O15118 1/20 0.44
MAPK13 O15264 1/20 0.44
MAPK12 P53778 1/20 0.44
MAPK11 Q15759 1/20 0.44
MAPK14 Q16539 1/20 0.44
HTT P42858 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL17543975 0.85 TSHR (0.61) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL28472780 0.83 CRBN (0.50) CRBNDDB1NPC1MAPK13MAPK12
Benzamide SCHEMBL28103386 0.82 TDP1 (0.64) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL28586624 0.81 CRBN (0.48) CRBNDDB1NPC1MAPK13MAPK12
Benzoic Acid SCHEMBL28099052 0.80 TSHR (0.54) CRBNDDB1NPC1MAPK13MAPK12
Benzoyl Peroxide SCHEMBL27773000 0.80 F2 (0.65) CRBNDDB1NPC1MAPK13MAPK12
SCHEMBL22028 0.79
Succinimide SCHEMBL6036901 0.79 CRBN (0.73) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL6717091 0.79 CRBN (0.73) CRBNDDB1NPC1MAPK13MAPK12
Succinimide SCHEMBL434236 0.79 CRBN (0.73) CRBNDDB1NPC1MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110381980-A The method that nucleic acid-peptide composition and inducing exon are skipped 艾维迪提生物科学有限责任公司 2019-10-25 CN disclosed
CN-109715805-A NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF 艾维迪提生物科学有限责任公司 2019-05-03 CN disclosed