Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL17543975 | 0.82 | TSHR (0.61) | TSHRTDP1ALDH1A1CRBNDDB1 | |
| Benzoyl Peroxide SCHEMBL3467853 | 0.81 | LMNA (1.00) | F2LMNATSHRTDP1ALDH1A1 | |
| Benzoyl Peroxide SCHEMBL2929886 | 0.81 | LMNA (1.00) | F2LMNATSHRTDP1ALDH1A1 | |
| Benzoyl Peroxide SCHEMBL9407293 | 0.81 | LMNA (1.00) | F2LMNATSHRTDP1ALDH1A1 | |
| Benzoyl Peroxide SCHEMBL63 | 0.81 | LMNA (1.00) | F2LMNATSHRTDP1ALDH1A1 | |
| Benzoyl Peroxide SCHEMBL5312311 | 0.81 | LMNA (1.00) | F2LMNATSHRTDP1ALDH1A1 | |
| Succinimide SCHEMBL28295942 | 0.80 | CRBN (0.46) | TSHRTDP1ALDH1A1HSD17B10CRBN | |
| Succinimide SCHEMBL28472780 | 0.79 | CRBN (0.50) | LMNATSHRTDP1ALDH1A1CRBN | |
| Benzoyl Peroxide SCHEMBL28318388 | 0.79 | LMNA (0.85) | F2LMNATSHRTDP1ALDH1A1 | |
| Benzoyl Peroxide SCHEMBL178097 | 0.79 | LMNA (0.94) | F2LMNATSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522699-A | Thioglucose spiroketal derivative and use thereof as therapeutic agent for diabetes | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2009-09-02 | — | — | CN | disclosed |
| CN-101495495-A | Substituted spiroketal derivative and use thereof as therapeutic agent for diabetes | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2009-07-29 | — | — | CN | disclosed |