Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163629 | 0.95 | MAPT (0.50) | MAPTLMNAERN1CYP17A1CYP21A2 | |
| SCHEMBL17923012 | 0.86 | CYP17A1 (0.67) | MAPTLMNAERN1CYP17A1CYP21A2 | |
| SCHEMBL3511526 | 0.82 | KIF11 (0.53) | MAPTLMNAERN1CYP17A1CYP21A2 | |
| SCHEMBL4732067 | 0.82 | CYP1A2 (0.53) | MAPTERN1CYP17A1SMN1; SMN2KDM4E | |
| SCHEMBL279908 | 0.81 | MAPT (0.55) | MAPTLMNAERN1CYP17A1CYP21A2 | |
| SCHEMBL302530 | 0.81 | TRIM24 (0.56) | MAPTLMNAERN1CYP17A1CYP11B1 | |
| SCHEMBL29534997 | 0.81 | TRIM24 (0.56) | MAPTLMNAERN1CYP17A1CYP11B1 | |
| SCHEMBL12068482 | 0.80 | MAPT (0.79) | MAPTLMNACYP17A1CYP21A2CYP11B1 | |
| SCHEMBL14426233 | 0.80 | MAPT (0.79) | MAPTLMNACYP17A1CYP21A2CYP11B1 | |
| SCHEMBL13915993 | 0.80 | MAPT (0.79) | MAPTLMNACYP17A1CYP21A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111621027-B | Preparation method and application of cationic porous material | 华南师范大学 | 2022-04-19 | — | — | CN | claimed |
| CN-109776534-A | Ratio sensing type zinc ion fluorescent and its preparation method and application | 山东理工大学 | 2019-05-21 | — | — | CN | claimed |
| CN-111621027-B | Preparation method and application of cationic porous material | 华南师范大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-109776534-A | Ratio sensing type zinc ion fluorescent and its preparation method and application | 山东理工大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-109776534-A | Ratio sensing type zinc ion fluorescent and its preparation method and application | 山东理工大学 | 2019-05-21 | — | — | CN | disclosed |