Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.31 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846091 | 0.78 | LRRK2 (0.42) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL30007698 | 0.78 | LRRK2 (0.42) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL1119092 | 0.75 | FFAR1 (0.42) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL245839 | 0.75 | CSNK1A1 (0.41) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL31321212 | 0.75 | CSNK1A1 (0.41) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL30211311 | 0.75 | LRRK2 (0.40) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL3287530 | 0.75 | LRRK2 (0.40) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL27810450 | 0.71 | BCL6 (0.37) | LRRK2ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL4475014 | 0.71 | KDM4E (0.40) | LRRK2ALDH1A1TDP1KMOCYP11B2 | |
| SCHEMBL25297122 | 0.71 | KDM4E (0.33) | LRRK2ALDH1A1NPSR1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843891-A | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2019-06-04 | — | — | CN | disclosed |