Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007698 | 1.00 | LRRK2 (0.42) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL15659375 | 0.78 | CYP11B2 (0.45) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL13074742 | 0.78 | LRRK2 (0.40) | LRRK2ALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL28296292 | 0.78 | LRRK2 (0.40) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL245839 | 0.78 | CSNK1A1 (0.41) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL30211311 | 0.78 | LRRK2 (0.40) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL1119092 | 0.78 | FFAR1 (0.42) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL3287530 | 0.78 | LRRK2 (0.40) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL31321212 | 0.78 | CSNK1A1 (0.41) | LRRK2ALDH1A1NPSR1TDP1KMT2A | |
| SCHEMBL4103795 | 0.77 | RXFP1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243164-A1 | PROCESS FOR PREPARING 2-[[5-(3-CHLOROPHENYL)-3-HYDROXYPYRIDINE-2-CARBONYL]AMINO]ACETIC ACID | AKEBIA THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| US-12269802-B2 | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino] acetic acid | AKEBIA THERAPEUTICS, INC. (US) | 2025-04-08 | — | — | US | disclosed |
| CN-115461334-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240158354-A1 | Process for Preparing 2-[[5-(3-Chlorophenyl)-3-Hydroxypyridine-2-Carbonyl]Amino]Acetic Acid | KREOS CAPITAL VII (UK) LIMITED (GB) | 2024-05-16 | — | — | US | disclosed |
| WO-2023160672-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LHOTSE BIO , INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| US-11713298-B2 | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid | AKEBIA THERAPEUTICS, INC. (US) | 2023-08-01 | — | — | US | disclosed |
| US-20230203004-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20230203004-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |
| WO-2006081072-A1 | ANTAGONISTS OF THE MGLU RECEPTOR AND USES THEREOF | ABBOTT LABORATORIES (US) | 2006-08-03 | — | — | WO | disclosed |
| EP-0795541-B1 | Method for production of nuclear halogenated aromatic compound possessing cyano groups | NIPPON CATALYTIC CHEM IND (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6034264-A | VAPOR PHASE REACTION; USING ACTIVATED CARBON AS CATALYST | NIPPON SHOKUBAI CO., LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| EP-0822930-B1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5789582-A | HALOGENATING CYANOAROMATIC COMPOUNDS IN THE VAPOR PHASE | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5763463-A | Pyridine compounds which are useful as pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0822930-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0795541-A1 | Method for production of nuclear halogenated aromatic compound possessing cyano groups | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996033975-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |
| US-4766219-A | Preparation of 2-cyano-6-chloropyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243164-A1 | PROCESS FOR PREPARING 2-[[5-(3-CHLOROPHENYL)-3-HYDROXYPYRIDINE-2-CARBONYL]AMINO]ACETIC ACID | AASDHPPT, AADAT, HPD | LRRK2 3194/4885ALDH1A1 39/4885NPSR1 3386/4885 |
| US-20230203004-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | ACE2, SIRT7, ACE | LRRK2 2611/4885ALDH1A1 1630/4885NPSR1 2407/4885 |
| US-11713298-B2 | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid | AASDHPPT, AADAT, ALDH7A1 | LRRK2 3682/4885ALDH1A1 15/4885NPSR1 2928/4885 |
| US-20240158354-A1 | Process for Preparing 2-[[5-(3-Chlorophenyl)-3-Hydroxypyridine-2-Carbonyl]Amino]Acetic Acid | AASDHPPT, AADAT, ALDH7A1 | LRRK2 3682/4885ALDH1A1 15/4885NPSR1 2928/4885 |
| US-12269802-B2 | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino] acetic acid | AASDHPPT, AADAT, ALDH7A1 | LRRK2 3682/4885ALDH1A1 15/4885NPSR1 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.