Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL27319836 | 0.82 | HTR2C (0.46) | ALDH1A1HSD17B10HPGDPARP1DRD2 | |
| Fluoranthene SCHEMBL27664070 | 0.81 | HSD17B10 (0.52) | ALDH1A1HSD17B10HPGDACHECYP3A4 | |
| Indoline SCHEMBL5629 | 0.80 | — | — | |
| Indoline SCHEMBL29360339 | 0.80 | — | — | |
| SCHEMBL6932843 | 0.78 | TSHR (0.41) | ALDH1A1HSD17B10CYP1A2HPGDCYP3A4 | |
| SCHEMBL29635644 | 0.78 | TSHR (0.41) | ALDH1A1HSD17B10CYP1A2HPGDCYP3A4 | |
| Indoline SCHEMBL23295083 | 0.78 | HTR2C (0.50) | ALDH1A1HSD17B10HPGDTSHRPARP1 | |
| Indoline SCHEMBL10723456 | 0.78 | HTR2C (0.50) | ALDH1A1HSD17B10HPGDTSHRPARP1 | |
| Indoline SCHEMBL2925258 | 0.78 | HTR2C (0.50) | ALDH1A1HSD17B10HPGDPARP1DRD2 | |
| Indoline SCHEMBL4903255 | 0.78 | HTR2C (0.50) | ALDH1A1HSD17B10HPGDTSHRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109648956-A | Photochromic material and preparation method thereof, application | 温州富奇士光电材料有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-105637416-B | Method for making photochromic optical articles using organic solvent pretreatment and photochromic coatings | 光学转变公司 | 2019-11-12 | — | — | CN | disclosed |