Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28963400 | 0.72 | PLA2G2D (0.43) | PLA2G2DLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL27993049 | 0.71 | LAP3 (0.43) | PLA2G2DLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL28264154 | 0.71 | LAP3 (0.50) | PLA2G2DLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL7554036 | 0.70 | PLA2G2C (0.51) | PLA2G2DLAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL23698927 | 0.69 | CYP3A4 (0.40) | PLA2G2DLAP3PLA2G2CGNAI3GNAO1 | |
| SCHEMBL7804496 | 0.69 | LPAR3 (0.53) | LAP3S1PR2S1PR1S1PR3SMPD1 | |
| SCHEMBL3147812 | 0.69 | LPAR3 (0.62) | PLA2G2DPLA2G2CSMPD1FDPSLPAR3 | |
| Dodecylamine SCHEMBL27738823 | 0.69 | LPAR3 (0.68) | LPAR3LPAR1LPAR2 | |
| SCHEMBL11155801 | 0.69 | LPAR3 (0.62) | PLA2G2DPLA2G2CSMPD1FDPSLPAR3 | |
| SCHEMBL2723071 | 0.69 | LPAR3 (0.62) | PLA2G2DPLA2G2CSMPD1FDPSLPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109913455-A | A kind of siRNA for capableing for the treatment of cancer | 宜春莲泽生物科技发展有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-106467915-B | SiRNA and its application and the method for inhibiting plk1 gene expression | 苏州瑞博生物技术有限公司 | 2019-06-04 | — | — | CN | disclosed |