SCHEMBL28296380

SCHEMBL28296380

CC(C)(C)OC(=O)C1(O)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
HPGD P15428 1/20 0.32
DGAT1 O75907 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.30
EIF2AK4 Q9P2K8 1/20 0.30
EPHX1 P07099 2/20 0.30
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20772092 0.93 CYP4F2 (0.33) CYP4F2CYP4A11DGAT1EIF2AK4CTSK
SCHEMBL10004931 0.89 MAPK1 (0.35) CYP4F2CYP4A11DGAT1
SCHEMBL6355124 0.80 NPSR1 (0.33) NPSR1CYP4F2CYP4A11HPGDDGAT1
SCHEMBL22098152 0.79 USP2 (0.43) CYP4F2CYP4A11
SCHEMBL28487708 0.79 KDM4E (0.33) CYP4F2CYP4A11KDM4E
SCHEMBL15114643 0.79 NPSR1 (0.34) NPSR1CYP4F2CYP4A11HPGD
SCHEMBL21564990 0.78 FFAR3 (0.37) NPSR1CYP4F2CYP4A11HPGDDGAT1
SCHEMBL15867797 0.78 CHRM2 (0.40) CYP4F2CYP4A11
SCHEMBL15867801 0.78 CHRM2 (0.40) CYP4F2CYP4A11
Hydrochloric Acid SCHEMBL6643227 0.78 KDM4E (0.32) CYP4F2CYP4A11KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824516-A A kind of preparation method of trans- -4- hydroxyl thiacyclohexane t-butyl formate 泰州精英化成医药科技有限公司 2019-05-31 CN disclosed