SCHEMBL28487708

SCHEMBL28487708

CC(C)(C)OC(=O)C1(O)CCNCC1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33
OPRM1 P35372 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6643227 0.98 KDM4E (0.32) KDM4EKMT2AOPRM1CYP4F2CYP4A11
SCHEMBL10004931 0.85 MAPK1 (0.35) KMT2ACYP4F2CYP4A11
SCHEMBL15055670 0.83 KDM4E (0.35) KDM4EKMT2AOPRM1CYP4F2CYP4A11
SCHEMBL20772092 0.81 CYP4F2 (0.33) CYP4F2CYP4A11
SCHEMBL13362182 0.81 KDM4E (0.32) KDM4EKMT2AOPRM1
SCHEMBL4372862 0.80 FFAR3 (0.34) KDM4EKMT2AOPRM1CYP4F2CYP4A11
SCHEMBL28296380 0.79 NPSR1 (0.32) KDM4ECYP4F2CYP4A11
SCHEMBL31333598 0.79 HRH3 (0.35) CYP4F2CYP4A11
Hydrochloric Acid SCHEMBL23211002 0.78 FFAR3 (0.33) KDM4EKMT2AOPRM1CYP4F2CYP4A11
SCHEMBL4372857 0.78 KDM4E (0.32) KDM4EKMT2AOPRM1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed
CN-112079830-B Inhibitor containing fused ring derivative, preparation method and application thereof 上海翰森生物医药科技有限公司 2023-12-22 CN disclosed
CN-112079830-A Fused ring-containing derivative inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2020-12-15 CN disclosed