Chloromethane

Chloromethane

SCHEMBL28296460

CCl.Oc1ccccc1-c1ccccc1O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
HPGD P15428 3/20 0.57
HSD17B10 Q99714 2/20 0.57
BCL2L1 Q07817 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MAPT P10636 2/20 0.53
RECQL P46063 2/20 0.53
CA2 P00918 2/20 0.53
NPC1 O15118 1/20 0.53
CA12 O43570 1/20 0.53
GMNN O75496 1/20 0.53
EGFR P00533 1/20 0.53
LMNA P02545 1/20 0.53
FYN P06241 1/20 0.53
POLB P06746 1/20 0.53
CA3 P07451 1/20 0.53
CYP3A4 P08684 1/20 0.53
MMP9 P14780 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30442890 0.90 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL28574 0.90 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL29623192 0.90 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Methyl Alcohol SCHEMBL1501092 0.88 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Hydrochloric Acid SCHEMBL31519864 0.87 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Catechol SCHEMBL21408977 0.87 ALDH1A1 (0.71) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL7845497 0.87 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Potassium SCHEMBL30932291 0.87 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Hydrogen Sulfide SCHEMBL20536042 0.87 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL477382 0.87 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110431195-A Antifouling composition JOTUN AS 2019-11-08 CN disclosed
CN-110128866-A The new dirt based on polysiloxanes controls coating system 汉伯公司 2019-08-16 CN disclosed
CN-110117464-A The new dirt based on polysiloxanes controls coating system 汉伯公司 2019-08-13 CN disclosed
CN-105143361-B Novel polysiloxane-based fouling control coating systems 汉伯公司 2019-06-04 CN disclosed