Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21528012 | 0.98 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL20553528 | 0.98 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL28564962 | 0.98 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL16334008 | 0.88 | SCN9A (0.32) | MAPK1 | |
| Pyrrole SCHEMBL28181367 | 0.88 | MAPT (0.31) | MAPK1 | |
| Pyridine SCHEMBL28861809 | 0.85 | BUB1 (0.33) | — | |
| SCHEMBL21001812 | 0.85 | — | — | |
| SCHEMBL6625570 | 0.85 | — | — | |
| SCHEMBL6625574 | 0.85 | — | — | |
| SCHEMBL5651571 | 0.82 | GABRP (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | disclosed |