Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | METAP1 | P53582 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 3/20 | 0.54 |
| ▸ | CCR5 | P51681 | 3/20 | 0.54 |
| ▸ | CCR8 | P51685 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | METAP2 | P50579 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL28307504 | 0.88 | SMN1; SMN2 (0.48) | KDM4EBLMRAB9ASMN1; SMN2NPC1 | |
| Benzimidazole SCHEMBL28471263 | 0.86 | SMN1; SMN2 (0.47) | KDM4EBLMRAB9ASMN1; SMN2NPC1 | |
| Benzimidazole SCHEMBL28467045 | 0.86 | SMN1; SMN2 (0.47) | KDM4EBLMRAB9ASMN1; SMN2NPC1 | |
| Benzimidazole SCHEMBL4894704 | 0.86 | SMN1; SMN2 (0.47) | KDM4EBLMRAB9ASMN1; SMN2NPC1 | |
| Benzimidazole SCHEMBL5133620 | 0.86 | SMN1; SMN2 (0.47) | KDM4EBLMRAB9ASMN1; SMN2NPC1 | |
| Benzimidazole SCHEMBL28472447 | 0.86 | SMN1; SMN2 (0.47) | KDM4EBLMRAB9ASMN1; SMN2NPC1 | |
| Benzimidazole SCHEMBL461969 | 0.85 | SMN1; SMN2 (0.50) | KDM4EBLMRAB9ASMN1; SMN2NPC1 | |
| Benzimidazole SCHEMBL29408372 | 0.85 | — | — | |
| Benzimidazole SCHEMBL29358377 | 0.85 | — | — | |
| Benzimidazole SCHEMBL10931770 | 0.85 | SMN1; SMN2 (0.50) | KDM4EBLMRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704989-A | A kind of synthetic method of O-phthalic nitrilic type acrylic ester monomer | 大连理工大学 | 2019-05-03 | — | — | CN | disclosed |