SCHEMBL28296638

SCHEMBL28296638

CC(C)(C)c1cc(OC(=O)CCC(O)CCCO)cc(C(C)(C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 11/20 0.53
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
GAA P10253 2/20 0.37
XBP1 P17861 1/20 0.37
ATM Q13315 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALOX5 P09917 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
ALOX15 P16050 2/20 0.34
GSR P00390 1/20 0.34
LMNA P02545 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28294458 0.89 VCAM1 (0.44) VCAM1CA1CA2GAAXBP1
SCHEMBL28220383 0.88 VCAM1 (0.44) VCAM1CA1CA2GAAXBP1
SCHEMBL28159896 0.82 VCAM1 (0.68) VCAM1CA1CA2GAAALOX15
SCHEMBL38445 0.80 VCAM1 (0.60) VCAM1CA1CA2GAAALOX5
SCHEMBL1577556 0.79 VCAM1 (0.61) VCAM1CA1CA2GAAALOX5
1,6-Hexanediol SCHEMBL1353108 0.77 VCAM1 (0.54) VCAM1CA1CA2GAAXBP1
SCHEMBL28853602 0.76 VCAM1 (0.54) VCAM1CA1CA2GAAXBP1
SCHEMBL28342245 0.76 VCAM1 (0.53) VCAM1CA1CA2GAAXBP1
SCHEMBL27695001 0.76 VCAM1 (0.52) VCAM1CA1CA2GAAALOX15
SCHEMBL4654670 0.76 VCAM1 (0.54) VCAM1CA1CA2GAAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105745313-B Lubricant oil composite 株式会社ADEKA 2019-05-28 CN disclosed