Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527709 | 0.91 | CA2 (0.62) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL165930 | 0.91 | CA2 (0.62) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| Ethylene Glycol SCHEMBL6231139 | 0.89 | CA2 (0.56) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| Ethylene Glycol SCHEMBL6230203 | 0.89 | CA2 (0.56) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| Methane SCHEMBL7998414 | 0.89 | CA2 (0.60) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL28029703 | 0.89 | CA2 (0.60) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| 1,3-Propanediol SCHEMBL6343516 | 0.86 | CA2 (0.52) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL6235820 | 0.84 | CA2 (0.50) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| SCHEMBL21382094 | 0.82 | CA2 (0.52) | ALDH1A1HPGDHSD17B10CA2CAMK2A | |
| Alcohol SCHEMBL28855015 | 0.81 | CA2 (0.83) | ALDH1A1HPGDHSD17B10CA2CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118258802-A | Quick detection method for qualitative and quantitative pathogenic microorganisms | 北京数字天眼生物科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-109807323-B | Silver cube/flower-shaped silicon dioxide core-shell nano material and preparation method and application thereof | 宁波工程学院 | 2021-03-02 | — | — | CN | claimed |
| CN-109807323-A | A kind of silver cube/flower-shaped silica core shell nanometer material and its preparation method and application | 宁波工程学院 | 2019-05-28 | — | — | CN | claimed |
| CN-118258802-A | Quick detection method for qualitative and quantitative pathogenic microorganisms | 北京数字天眼生物科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118258802-A | Quick detection method for qualitative and quantitative pathogenic microorganisms | 北京数字天眼生物科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-109807323-B | Silver cube/flower-shaped silicon dioxide core-shell nano material and preparation method and application thereof | 宁波工程学院 | 2021-03-02 | — | — | CN | disclosed |
| CN-109807323-B | Silver cube/flower-shaped silicon dioxide core-shell nano material and preparation method and application thereof | 宁波工程学院 | 2021-03-02 | — | — | CN | disclosed |
| CN-109807323-A | A kind of silver cube/flower-shaped silica core shell nanometer material and its preparation method and application | 宁波工程学院 | 2019-05-28 | — | — | CN | disclosed |
| CN-109807323-A | A kind of silver cube/flower-shaped silica core shell nanometer material and its preparation method and application | 宁波工程学院 | 2019-05-28 | — | — | CN | disclosed |