SCHEMBL28296681

SCHEMBL28296681

O=CC(C=O)=Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
TSHR P16473 1/20 0.60
CYP2A6 P11509 1/20 0.50
AKR1C3 P42330 1/20 0.48
AKR1C1 Q04828 1/20 0.46
LMNA P02545 3/20 0.46
TDP1 Q9NUW8 2/20 0.44
FBP1 P09467 3/20 0.43
MAPK1 P28482 2/20 0.42
TRPA1 O75762 1/20 0.42
ALOX5 P09917 1/20 0.42
CYP2C9 P11712 2/20 0.42
CYP3A4 P08684 1/20 0.42
PRMT1 Q99873 1/20 0.42
ESR1 P03372 1/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10643212 0.86 ALDH1A1 (0.52) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1
SCHEMBL7167811 0.84 ALDH1A1 (0.55) ALDH1A1TSHRLMNATDP1MAPK1
SCHEMBL155213 0.79 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1
SCHEMBL1759350 0.79 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1
SCHEMBL6331873 0.79 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1
SCHEMBL6331875 0.79 ALDH1A1 (0.60) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1
SCHEMBL25263515 0.78 ALDH1A1 (0.53) ALDH1A1TSHRCYP2A6AKR1C3LMNA
Hydrogen Sulfide SCHEMBL28269184 0.77 ALDH1A1 (0.58) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1
SCHEMBL28532750 0.77 ALDH1A1 (0.58) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1
SCHEMBL567062 0.75 ALDH1A1 (0.56) ALDH1A1TSHRCYP2A6AKR1C3AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1994309-A Use of caryophyllene compound composition in medicine for treating general anxiety neurosis and depression ZHENG LEJIAN (CN) 2007-07-11 CN claimed
CN-119307205-A Formaldehyde-free adhesive for artificial board and preparation method thereof 山东顺创新材料科技有限公司 2025-01-14 CN disclosed
CN-109666163-B Hybrid crosslinked dynamic polymer and application thereof 厦门逍扬运动科技有限公司 2023-05-12 CN disclosed
CN-109666162-A A kind of energy-absorbing method based on dynamic crosslinking polymer 翁秋梅 2019-04-23 CN disclosed
CN-104043066-A Chinese herbal medicine extract for promoting hair growth, blackening hair and improving dandruff and application thereof JI TINGHUANG 2014-09-17 CN disclosed