Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863067 | 0.95 | TSHR (0.60) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28295220 | 0.93 | TSHR (0.57) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28654888 | 0.91 | ALDH1A1 (0.53) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28902553 | 0.91 | TSHR (0.61) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28902535 | 0.90 | ALDH1A1 (0.62) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28902543 | 0.90 | ALDH1A1 (0.62) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28511326 | 0.90 | ALDH1A1 (0.62) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28706598 | 0.90 | ALDH1A1 (0.62) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL28308702 | 0.90 | ALDH1A1 (0.62) | TSHRTDP1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL17223287 | 0.89 | TSHR (0.55) | TSHRRAB9AMAPK1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109679300-A | Thermoplastic polyester complex and preparation method thereof, product | 中国科学院宁波材料技术与工程研究所 | 2019-04-26 | — | — | CN | claimed |
| CN-109679300-A | Thermoplastic polyester complex and preparation method thereof, product | 中国科学院宁波材料技术与工程研究所 | 2019-04-26 | — | — | CN | disclosed |