Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185804 | 0.83 | KMT2A (0.59) | RXFP1SMN1; SMN2P2RX1KMT2APTGS1 | |
| SCHEMBL2186132 | 0.83 | P2RX1 (0.55) | RXFP1SMN1; SMN2P2RX1KMT2APTGS1 | |
| SCHEMBL4147912 | 0.81 | P2RX1 (0.56) | RXFP1SMN1; SMN2P2RX1KMT2APTGS1 | |
| SCHEMBL2211815 | 0.81 | KMT2A (0.58) | RXFP1P2RX1KMT2APTGS1MAPT | |
| SCHEMBL12544169 | 0.80 | RXFP1 (0.88) | RXFP1SMN1; SMN2P2RX1KMT2APTGS1 | |
| SCHEMBL14394718 | 0.79 | P2RX1 (0.78) | RXFP1SMN1; SMN2P2RX1KMT2APTGS1 | |
| SCHEMBL11344615 | 0.78 | NAMPT (0.68) | SMN1; SMN2KMT2AMAPTHSD17B10NAMPT | |
| SCHEMBL22066205 | 0.78 | RXFP1 (0.79) | RXFP1SMN1; SMN2P2RX1KMT2APTGS1 | |
| SCHEMBL16127831 | 0.78 | RXFP1 (0.76) | RXFP1P2RX1PTGS1MAPT | |
| SCHEMBL28103851 | 0.78 | RXFP1 (0.57) | RXFP1SMN1; SMN2P2RX1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960400-B | Sulfamoylthiophene amide derivatives and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-05-31 | — | — | CN | disclosed |