Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211815 | 0.90 | KMT2A (0.58) | KMT2AMEN1RAB9ANPC1P2RX1 | |
| SCHEMBL28297049 | 0.83 | RXFP1 (0.62) | KMT2AMEN1RAB9AP2RX1RXFP1 | |
| SCHEMBL2186132 | 0.81 | P2RX1 (0.55) | KMT2AMEN1RAB9AP2RX1RXFP1 | |
| SCHEMBL2186276 | 0.80 | DHODH (0.82) | KMT2AMEN1RAB9ANPC1RXFP1 | |
| SCHEMBL4147912 | 0.80 | P2RX1 (0.56) | KMT2AMEN1P2RX1RXFP1PTGS1 | |
| SCHEMBL7814990 | 0.80 | P2RX1 (0.74) | KMT2AMEN1RAB9AP2RX1RXFP1 | |
| SCHEMBL2186500 | 0.79 | KMT2A (0.55) | KMT2AMEN1RAB9ANPC1P2RX1 | |
| SCHEMBL29732982 | 0.76 | RXFP1 (0.80) | KMT2AMEN1RAB9ANPC1RXFP1 | |
| SCHEMBL12443603 | 0.76 | RXFP1 (0.80) | KMT2AMEN1RAB9ANPC1RXFP1 | |
| SCHEMBL8461120 | 0.75 | MAPT (0.75) | KMT2AMEN1RAB9ANPC1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |