SCHEMBL28297057

SCHEMBL28297057

CC(C)(c1ccc2ccccc2c1)C(C)(C)c1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.48
CYP2A6 P11509 7/20 0.48
TDP1 Q9NUW8 1/20 0.48
CASR P41180 1/20 0.45
CYP1A2 P05177 4/20 0.44
CYP3A4 P08684 3/20 0.44
CYP2D6 P10635 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
KCNH2 Q12809 2/20 0.44
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
ALOX12 P18054 1/20 0.40
UGT2B7 P16662 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295496 0.93 CYP3A4 (0.44) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL599567 0.85 PTPN1 (0.48) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL30222062 0.85 PTPN1 (0.48) PTPN1CYP2A6TDP1CASRCYP1A2
Ammonia Solution, Strong SCHEMBL29065748 0.82 CYP2A6 (0.42) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL8902613 0.81 PTPN1 (0.46) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL9274665 0.81 CASR (0.46) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL13704976 0.81 PTPN1 (0.46) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL19718548 0.81 PTPN1 (0.46) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL548731 0.81 PTPN1 (0.50) PTPN1CYP2A6TDP1CASRCYP1A2
SCHEMBL7132144 0.81 CASR (0.58) PTPN1CYP2A6TDP1CASRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109734959-A A kind of heat-resistance type radical initiator and its preparation method and application 清远市普塞呋磷化学有限公司 2019-05-10 CN disclosed