Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625553 | 0.90 | RARB (0.45) | RARBRARGHCAR3TP53TSHR | |
| SCHEMBL28246187 | 0.90 | RARB (0.45) | RARBRARGHCAR3TP53TSHR | |
| Iodide SCHEMBL515607 | 0.89 | RARB (0.44) | RARBRARGHCAR3TP53TSHR | |
| SCHEMBL8597288 | 0.76 | CNR2 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL28246754 | 0.76 | CNR2 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL10495082 | 0.76 | CNR2 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL3867447 | 0.75 | GNRHR (0.38) | RARBRARGHCAR3KDM4EGAA | |
| Iodide SCHEMBL2495397 | 0.75 | CNR2 (0.39) | KDM4EALDH1A1 | |
| Iodide SCHEMBL2498701 | 0.75 | CNR2 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL29870539 | 0.74 | POLB (0.40) | RARBRARGHCAR3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417670-B | A kind of near-infrared squarylium cyanine dyes probe and its preparation method and application based on thymidine | 常州大学 | 2019-06-04 | — | — | CN | claimed |
| CN-107417670-B | A kind of near-infrared squarylium cyanine dyes probe and its preparation method and application based on thymidine | 常州大学 | 2019-06-04 | — | — | CN | disclosed |