Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28246187 | 0.99 | RARB (0.45) | RARBRARGHCAR3TP53TSHR | |
| SCHEMBL29625553 | 0.99 | RARB (0.45) | RARBRARGHCAR3TP53TSHR | |
| SCHEMBL28297367 | 0.89 | RARB (0.43) | RARBRARGHCAR3TP53TSHR | |
| SCHEMBL3867447 | 0.84 | GNRHR (0.38) | RARBRARGHCAR3KDM4EGAA | |
| SCHEMBL28642778 | 0.83 | POLB (0.40) | RARBRARGHCAR3KDM4EALDH1A1 | |
| SCHEMBL29870539 | 0.83 | POLB (0.40) | RARBRARGHCAR3KDM4EALDH1A1 | |
| SCHEMBL3868601 | 0.82 | GNRHR (0.39) | RARBRARGHCAR3KDM4EGAA | |
| SCHEMBL17838804 | 0.82 | GNRHR (0.39) | RARBRARGHCAR3KDM4EGAA | |
| Iodide SCHEMBL27878164 | 0.81 | LMNA (0.35) | TSHRKDM4EALDH1A1MEN1KDM4A | |
| Iodide SCHEMBL28003613 | 0.80 | MEN1 (0.38) | TP53TSHRALDH1A1MEN1KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637680-B2 | Dye-sensitized solar cell, photoelectric conversion element, and dye for use in the solar cell and the element | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2014-01-28 | — | — | US | disclosed |
| US-20120029206-A1 | DYE-SENSITIZED SOLAR CELL, PHOTOELECTRIC CONVERSION ELEMENT, AND DYE FOR USE IN THE SOLAR CELL AND THE ELEMENT | NATIONAL UNIVERSITY CORPORATION KYUSHU INSTITUTE OF TECHNOLOGY (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2408058-A1 | DYE-SENSITIZED SOLAR CELL, PHOTOELECTRIC CONVERSION ELEMENT, AND DYE FOR USE IN THE SOLAR CELL AND THE ELEMENT | Nippon Steel Chemical Co., Ltd. (JP) | 2012-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029206-A1 | DYE-SENSITIZED SOLAR CELL, PHOTOELECTRIC CONVERSION ELEMENT, AND DYE FOR USE IN THE SOLAR CELL AND THE ELEMENT | CRY1, CRY2, SQLE | RARB 480/4885RARG 270/4885HCAR3 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.