Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | OSBP | P22059 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | UGCG | Q16739 | 2/20 | 0.49 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30650078 | 1.00 | DPP4 (0.73) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL30652021 | 1.00 | DPP4 (0.73) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL30650719 | 1.00 | DPP4 (0.73) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL30651191 | 1.00 | DPP4 (0.73) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL30650273 | 0.99 | DPP4 (0.72) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL30652963 | 0.99 | DPP4 (0.72) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL30652618 | 0.99 | DPP4 (0.72) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL30651608 | 0.99 | DPP4 (0.72) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL12207653 | 0.96 | DPP4 (0.76) | DPP4POLBPOLA1PTPN7DUSP3 | |
| SCHEMBL9978568 | 0.96 | DPP4 (0.76) | DPP4POLBPOLA1PTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100062023-A1 | CHOLESTEROL-CONTAINING COMPOUNDS AND THEIR USE AS IMMUNOGENS AGAINST BORRELIA BURGDORFERI | The Government of the United States of America as represented by the Secretary, Department of | 2010-03-11 | — | — | US | claimed |
| EP-2030979-A1 | Cholesterol-containing compounds and their use as immunogens against borrelia burgdorferi | The Government of the United States of America as Represented by The Department of Health and Human Services (US) | 2009-03-04 | — | — | EP | claimed |
| US-20100062023-A1 | CHOLESTEROL-CONTAINING COMPOUNDS AND THEIR USE AS IMMUNOGENS AGAINST BORRELIA BURGDORFERI | The Government of the United States of America as represented by the Secretary, Department of | 2010-03-11 | — | — | US | disclosed |
| US-7666846-B2 | a conjugate of chloesterol containing compound having a sugar moiety containing methyl esteralkyleneazide group and a carrier protein; produce an effective vaccine to prevent Lyme disease | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-02-23 | — | — | US | disclosed |
| EP-2030979-A1 | Cholesterol-containing compounds and their use as immunogens against borrelia burgdorferi | The Government of the United States of America as Represented by The Department of Health and Human Services (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20060204515-A1 | Cholesterol-containing compounds and their use as immunogens against borrelia burgdorferi | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2006-09-14 | — | — | US | disclosed |
| EP-1613641-A2 | CHOLESTEROL-CONTAINING COMPOUNDS AND THEIR USE AS IMMUNOGENS AGAINST BORRELIA BURGDORFERI | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004089969-A2 | CHOLESTEROL-CONTAINING COMPOUNDS AND THEIR USE AS IMMUNOGENS AGAINST BORRELIA BURGDORFERI | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTHAND HUMAN SERVICES (US) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060204515-A1 | Cholesterol-containing compounds and their use as immunogens against borrelia burgdorferi | LCAT, APOB, CETP | DPP4 2742/4885POLB 4104/4885POLA1 4388/4885 |
| US-20100062023-A1 | CHOLESTEROL-CONTAINING COMPOUNDS AND THEIR USE AS IMMUNOGENS AGAINST BORRELIA BURGDORFERI | LCAT, APOB, CETP | DPP4 2742/4885POLB 4104/4885POLA1 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.