Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995962 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL28297775 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL16432175 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL16431977 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL21527897 | 0.80 | MEN1 (0.49) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL20002692 | 0.80 | MEN1 (0.49) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL19995889 | 0.80 | MEN1 (0.49) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL21527909 | 0.79 | HCAR2 (0.44) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL19995539 | 0.79 | HCAR2 (0.44) | ALDH1A1MEN1KMT2APDE4APDE4B | |
| SCHEMBL19996130 | 0.78 | MEN1 (0.41) | ALDH1A1MEN1KMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715633-A | Dopamine-B-hydroxylase inhibitors | 巴尔-波特拉及康邦亚股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109715155-A | blood brain barrier-penetrating agent dopamine- β -hydroxylase inhibitors | 巴尔-波特拉及康邦亚股份有限公司 | 2019-05-03 | — | — | CN | disclosed |