SCHEMBL2829783

SCHEMBL2829783

CC(CCCOc1c(C(C)(C)C)cc(Cc2cc(C(C)(C)C)c(OCCCC(C)C3CO3)c(C(C)(C)C)c2)cc1C(C)(C)C)C1CO1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
DHFR P00374 1/20 0.32
SCN2A Q99250 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2830421 0.92 CYP3A4 (0.40) CYP3A4CYP2D6SCN2A
SCHEMBL2836817 0.89 CYP3A4 (0.41) CYP3A4CYP2D6
SCHEMBL2830476 0.89 CYP3A4 (0.30) CYP3A4CYP2D6
SCHEMBL2831521 0.89 CYP3A4 (0.30) CYP3A4CYP2D6
SCHEMBL2829886 0.87 CYP3A4 (0.40) CYP3A4CYP2D6
SCHEMBL2830479 0.86 CNR1 (0.30)
SCHEMBL2834161 0.85 CYP3A4 (0.36) CYP3A4CYP2D6DHFR
SCHEMBL2829969 0.84 CYP3A4 (0.35) CYP3A4CYP2D6DHFR
SCHEMBL2831159 0.84 CYP3A4 (0.35) CYP3A4CYP2D6DHFR
SCHEMBL2834983 0.82 HTR1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100160555-A1 RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-24 US disclosed
EP-2133380-A1 RESIN COMPOSITION Sumitomo Chemical Company, Limited (JP) 2009-12-16 EP disclosed