SCHEMBL28297856

SCHEMBL28297856

O=C(O)c1cncc(O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 3/20 0.41
CA1 P00915 5/20 0.39
CA2 P00918 5/20 0.39
CA12 O43570 4/20 0.39
CA7 P43166 4/20 0.39
CA9 Q16790 4/20 0.39
CA14 Q9ULX7 4/20 0.39
ALDH1A1 P00352 6/20 0.38
HPGD P15428 2/20 0.38
HMGB1 P09429 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
THRB P10828 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23853877 0.85 CA12 (0.52) KDM4EKMT2ACA1CA2CA12
SCHEMBL1171212 0.85 KDM4E (0.47) KDM4EKMT2ACA1CA2CA12
SCHEMBL593852 0.85 KMT2A (0.39) KDM4EKMT2ACA1CA2CA12
SCHEMBL7067360 0.81 SELL (0.50) KDM4EKMT2ACA1CA2CA12
SCHEMBL28194744 0.81 TSHR (0.43) KDM4EKMT2ACA1CA2CA12
SCHEMBL28194746 0.81 CA12 (0.46) KDM4EKMT2ACA1CA2CA12
Nitrous Acid SCHEMBL28558486 0.77 KDM4E (0.41) KDM4EKMT2AALDH1A1SMN1; SMN2NAPRT
SCHEMBL1245001 0.76 KDM4E (0.53) KDM4EKMT2AALDH1A1HPGDNAPRT
SCHEMBL21749937 0.76 HCAR2 (0.41) KDM4EKMT2ACA1CA2CA12
SCHEMBL28378544 0.76 KDM4E (0.48) KDM4EKMT2AALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109836373-A A kind of environmentally friendly method prepared and circulation of tail gas utilizes of vitamin B6 新发药业有限公司 2019-06-04 CN disclosed
CN-109836374-A A kind of vitamin B6Environment-friendly preparation method 新发药业有限公司 2019-06-04 CN disclosed