Nitrous Acid

Nitrous Acid

SCHEMBL28558486

O=C(O)c1cncc(C(=O)O)c1C(=O)O.O=NO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.41
KMT2A Q03164 4/20 0.41
ALDH1A1 P00352 6/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 2/20 0.36
KDM4C Q9H3R0 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM6B O15054 1/20 0.36
KDM4A O75164 1/20 0.36
THRB P10828 1/20 0.36
KDM4D Q6B0I6 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ASPH Q12797 2/20 0.35
KDM8 Q8N371 2/20 0.35
HCAR2 Q8TDS4 6/20 0.34
ALOX15 P16050 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33
AGER Q15109 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1171212 0.91 KDM4E (0.47) KDM4EKMT2AALDH1A1MEN1MAPT
SCHEMBL28558485 0.81 KMT2A (0.35) KDM4EKMT2AALDH1A1MEN1MAPT
SCHEMBL28297856 0.77 KDM4E (0.41) KDM4EKMT2AALDH1A1MEN1MAPT
Nitrous Acid SCHEMBL28696829 0.76 HCAR2 (0.41) KDM4EKMT2AALDH1A1MEN1HCAR2
SCHEMBL1245001 0.76 KDM4E (0.53) KDM4EKMT2AALDH1A1MEN1MAPT
SCHEMBL28378544 0.76 KDM4E (0.48) KDM4EKMT2AALDH1A1MEN1KDM4C
SCHEMBL21749937 0.76 HCAR2 (0.41) KDM4EKMT2AALDH1A1MEN1MAPT
Nitrous Acid SCHEMBL28928125 0.76 HCAR2 (0.41) KDM4EKMT2AALDH1A1MEN1MAPT
SCHEMBL28723383 0.72 KDM4E (0.43) KDM4EKMT2AALDH1A1MEN1MAPT
SCHEMBL20512962 0.70 SELL (0.42) KDM4EKMT2AALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415457-B Method for preparing functionalized polymers 株式会社普利司通 2021-05-25 CN disclosed