Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 11/20 | 0.64 |
| ▸ | PRKCB | P05771 | 11/20 | 0.64 |
| ▸ | PRKCA | P17252 | 11/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 11/20 | 0.64 |
| ▸ | PRKCH | P24723 | 10/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 10/20 | 0.64 |
| ▸ | CAMK2D | Q13557 | 9/20 | 0.64 |
| ▸ | CAMK2B | Q13554 | 8/20 | 0.64 |
| ▸ | CAMK2G | Q13555 | 8/20 | 0.64 |
| ▸ | CAMK2A | Q9UQM7 | 8/20 | 0.64 |
| ▸ | PRKCZ | Q05513 | 7/20 | 0.64 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.64 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.64 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.64 |
| ▸ | STK16 | O75716 | 1/20 | 0.64 |
| ▸ | PAK3 | O75914 | 1/20 | 0.64 |
| ▸ | CDK14 | O94921 | 1/20 | 0.64 |
| ▸ | MET | P08581 | 1/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27993565 | 0.99 | PRKCG (0.65) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Hydrochloric Acid SCHEMBL29784988 | 0.84 | PRKCG (0.77) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL29356867 | 0.79 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL678748 | 0.79 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL29371538 | 0.79 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL16934851 | 0.78 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL4325665 | 0.78 | PRKCG (0.98) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL4877354 | 0.78 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL29371570 | 0.78 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL23299739 | 0.76 | PRKCG (0.68) | PRKCGPRKCBPRKCAPRKCEPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952383-A | Methods and compositions for predicting enzastaurin activity | 索元生物医药有限公司 | 2019-06-28 | — | — | CN | disclosed |