Benzimidazole

Benzimidazole

SCHEMBL28297947

CCCCCl.c1ccc2[nH]cnc2c1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
BCHE P06276 1/20 0.40
TRPC3 Q13507 1/20 0.40
TRPC4 Q9UBN4 1/20 0.40
TRPC5 Q9UL62 1/20 0.40
EPHX1 P07099 1/20 0.39
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MMP12 P39900 1/20 0.38
QPCT Q16769 2/20 0.37
CTNNB1 P35222 1/20 0.37
WNT3A P56704 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
PDPK1 O15530 1/20 0.37
CA12 O43570 1/20 0.37
PARP1 P09874 1/20 0.37
ALOX15 P16050 1/20 0.37
CA9 Q16790 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL9039906 0.93 EPHX1 (0.43) RAB9ANPC1BCHETRPC3TRPC4
Benzimidazole SCHEMBL28179791 0.91 EPHX1 (0.45) RAB9ANPC1BCHETRPC3TRPC4
Benzimidazole SCHEMBL28305285 0.89 EPHX1 (0.47) RAB9ANPC1BCHETRPC3TRPC4
Decane SCHEMBL18837832 0.89 EPHX1 (0.47) RAB9ANPC1BCHETRPC3TRPC4
Benzimidazole SCHEMBL28305296 0.89 EPHX1 (0.47) RAB9ANPC1BCHETRPC3TRPC4
Decane SCHEMBL9488659 0.88 EPHX1 (0.46) RAB9ANPC1BCHETRPC3TRPC4
Benzimidazole SCHEMBL29285060 0.87 MMP12 (0.43) RAB9ANPC1MMP12QPCTCTNNB1
Benzimidazole SCHEMBL3181865 0.85 MMP12 (0.44) RAB9ANPC1TDP1MMP12QPCT
Benzimidazole SCHEMBL8010735 0.85 MMP12 (0.44) RAB9ANPC1TDP1MMP12QPCT
Benzimidazole SCHEMBL28206119 0.85 SMN1; SMN2 (0.44) RAB9ANPC1TDP1MMP12QPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037275-B The method for preparing Zilpaterol and its salt 英特威国际有限公司 2019-05-10 CN disclosed