Phenol

Phenol

SCHEMBL28298044

Cc1ccccc1Br.Oc1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.71
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
GLA P06280 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA9 Q16790 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ACHE P22303 2/20 0.41
TSHR P16473 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
ESR1 P03372 6/20 0.38
ESR2 Q92731 6/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9840 0.84
SCHEMBL14127433 0.84
SCHEMBL29427037 0.84
SCHEMBL29077748 0.82
Ammonia Solution, Strong SCHEMBL4260010 0.82
O-Xylene SCHEMBL467845 0.82 CA12 (0.69) ALDH1A1CA12CA1CA2GLA
Bromide SCHEMBL29030286 0.82 ALDH1A1 (0.94) ALDH1A1CA1CA2CA4CA9
Phosphine SCHEMBL9803033 0.82
SCHEMBL1314410 0.82
Bromobenzene SCHEMBL594876 0.80 ALDH1A1 (0.79) ALDH1A1CA1CA2CA9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109761759-A A kind of brominated method of high regioselectivity of phenol compound 信阳师范学院 2019-05-17 CN disclosed