Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298068 | 0.76 | HRH3 (0.46) | HRH3HRH4HRH1L3MBTL1TSHR | |
| SCHEMBL41191 | 0.72 | L3MBTL1 (0.59) | HRH3HRH4HRH1L3MBTL1TSHR | |
| SCHEMBL29830938 | 0.72 | L3MBTL1 (0.59) | HRH3HRH4HRH1L3MBTL1TSHR | |
| SCHEMBL9953712 | 0.71 | L3MBTL1 (0.50) | HRH3HRH4HRH1L3MBTL1LMNA | |
| SCHEMBL29715188 | 0.70 | L3MBTL1 (0.57) | HRH3HRH4HRH1L3MBTL1TSHR | |
| Ammonia Solution, Strong SCHEMBL6176560 | 0.70 | L3MBTL1 (0.57) | HRH3HRH4HRH1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL10884973 | 0.70 | L3MBTL1 (0.57) | HRH3HRH4HRH1L3MBTL1LMNA | |
| Bromide SCHEMBL6114859 | 0.70 | L3MBTL1 (0.57) | HRH3HRH4HRH1L3MBTL1TSHR | |
| SCHEMBL4938201 | 0.70 | L3MBTL1 (0.57) | HRH3HRH4HRH1L3MBTL1TSHR | |
| SCHEMBL4938207 | 0.70 | L3MBTL1 (0.57) | HRH3HRH4HRH1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843891-A | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2019-06-04 | — | — | CN | disclosed |