Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007112 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1POLBLRRK2KMO | |
| SCHEMBL30692909 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1POLBLRRK2KMO | |
| SCHEMBL26686534 | 0.72 | USP7 (0.35) | GAAMAPT | |
| SCHEMBL24257639 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1POLB | |
| SCHEMBL28296285 | 0.71 | LRRK2 (0.36) | KDM4EALDH1A1LRRK2MEN1GAA | |
| SCHEMBL19798188 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1POLBLRRK2KMO | |
| SCHEMBL29672973 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1POLBLRRK2KMO | |
| SCHEMBL31727717 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1POLBLRRK2KMO | |
| SCHEMBL14783084 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1POLBLRRK2KMO | |
| SCHEMBL3095407 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1POLBLRRK2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843891-A | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2019-06-04 | — | — | CN | disclosed |